Impact of Direction of Transport on the Evaluation of Inhibition Potencies of Multidrug and Toxin Extrusion Protein 1 Inhibitors
![When Does the IC50 Accurately Assess the Blocking Potency of a Drug? | Journal of Chemical Information and Modeling When Does the IC50 Accurately Assess the Blocking Potency of a Drug? | Journal of Chemical Information and Modeling](https://pubs.acs.org/cms/10.1021/acs.jcim.9b01085/asset/images/medium/ci9b01085_0003.gif)
When Does the IC50 Accurately Assess the Blocking Potency of a Drug? | Journal of Chemical Information and Modeling
![The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments | Drug Metabolism & Disposition The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments | Drug Metabolism & Disposition](https://dmd.aspetjournals.org/content/dmd/43/11/1744/F2.large.jpg)
The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments | Drug Metabolism & Disposition
![IC50 values of parasite treated with the drug were determined using the... | Download Scientific Diagram IC50 values of parasite treated with the drug were determined using the... | Download Scientific Diagram](https://www.researchgate.net/profile/Paul-Jensen-6/publication/51399888/figure/fig1/AS:202681709797376@1425334493286/IC50-values-of-parasite-treated-with-the-drug-were-determined-using-the-SYBR-Green-assay.png)
IC50 values of parasite treated with the drug were determined using the... | Download Scientific Diagram
![A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient | Scientific Reports A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fsrep29387/MediaObjects/41598_2016_Article_BFsrep29387_Fig1_HTML.jpg)
A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient | Scientific Reports
![Cell viability curves and IC50 values (concentration responsible for... | Download Scientific Diagram Cell viability curves and IC50 values (concentration responsible for... | Download Scientific Diagram](https://www.researchgate.net/profile/Jose-Almeida-Bezerra/publication/338838859/figure/fig3/AS:851947905101825@1580131617971/Cell-viability-curves-and-IC50-values-concentration-responsible-for-50-colony-growth.jpg)
Cell viability curves and IC50 values (concentration responsible for... | Download Scientific Diagram
![The advantages of describing covalent inhibitor in vitro potencies by IC50 at a fixed time point. IC50 determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization - ScienceDirect The advantages of describing covalent inhibitor in vitro potencies by IC50 at a fixed time point. IC50 determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0968089620306957-gr1.jpg)
The advantages of describing covalent inhibitor in vitro potencies by IC50 at a fixed time point. IC50 determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization - ScienceDirect
![Evaluation of IC50 levels immediately after treatment with anticancer reagents using a real‑time cell monitoring device Evaluation of IC50 levels immediately after treatment with anticancer reagents using a real‑time cell monitoring device](https://www.spandidos-publications.com/article_images/etm/18/4/etm-18-04-3197-g02.jpg)
Evaluation of IC50 levels immediately after treatment with anticancer reagents using a real‑time cell monitoring device
![Comparison of mushroom tyrosinase inhibitory abilities (IC50) among... | Download Scientific Diagram Comparison of mushroom tyrosinase inhibitory abilities (IC50) among... | Download Scientific Diagram](https://www.researchgate.net/publication/271221177/figure/fig5/AS:271595549753351@1441764833215/Comparison-of-mushroom-tyrosinase-inhibitory-abilities-IC50-among-kojic-acid-arbutin.png)
Comparison of mushroom tyrosinase inhibitory abilities (IC50) among... | Download Scientific Diagram
![Half maximal inhibitory concentration (IC50). IC50 value was determined... | Download Scientific Diagram Half maximal inhibitory concentration (IC50). IC50 value was determined... | Download Scientific Diagram](https://www.researchgate.net/profile/Jongbae-Kim/publication/270962245/figure/fig5/AS:267766326362146@1440851875575/Half-maximal-inhibitory-concentration-IC50-IC50-value-was-determined-by-the-broth.png)
Half maximal inhibitory concentration (IC50). IC50 value was determined... | Download Scientific Diagram
![The 50% inhibitory concentration (IC50) values of oxaliplatin and NC-4016. | Download Scientific Diagram The 50% inhibitory concentration (IC50) values of oxaliplatin and NC-4016. | Download Scientific Diagram](https://www.researchgate.net/profile/Satoru-Kondo/publication/263514704/figure/fig1/AS:214060948824068@1428047515563/The-50-inhibitory-concentration-IC50-values-of-oxaliplatin-and-NC-4016.png)
The 50% inhibitory concentration (IC50) values of oxaliplatin and NC-4016. | Download Scientific Diagram
![RTCA measurement of IC50 value of A) mangiferin, B) hesperidin and C)... | Download Scientific Diagram RTCA measurement of IC50 value of A) mangiferin, B) hesperidin and C)... | Download Scientific Diagram](https://www.researchgate.net/profile/Rafal-Bartoszewski/publication/260842114/figure/fig11/AS:669586848497678@1536653353911/RTCA-measurement-of-IC50-value-of-A-mangiferin-B-hesperidin-and-C-hesperidin-in-the_Q320.jpg)
RTCA measurement of IC50 value of A) mangiferin, B) hesperidin and C)... | Download Scientific Diagram
![Figure 6, IC50 Curve for Probe Compound as determined by gel-based competitive-ABPP with FP-Rh (AID 463124) - Probe Reports from the NIH Molecular Libraries Program - NCBI Bookshelf Figure 6, IC50 Curve for Probe Compound as determined by gel-based competitive-ABPP with FP-Rh (AID 463124) - Probe Reports from the NIH Molecular Libraries Program - NCBI Bookshelf](https://www.ncbi.nlm.nih.gov/books/NBK98922/bin/ml174f6.jpg)
Figure 6, IC50 Curve for Probe Compound as determined by gel-based competitive-ABPP with FP-Rh (AID 463124) - Probe Reports from the NIH Molecular Libraries Program - NCBI Bookshelf
![When Does the IC50 Accurately Assess the Blocking Potency of a Drug? | Journal of Chemical Information and Modeling When Does the IC50 Accurately Assess the Blocking Potency of a Drug? | Journal of Chemical Information and Modeling](https://pubs.acs.org/cms/10.1021/acs.jcim.9b01085/asset/images/large/ci9b01085_0007.jpeg)